Welcome to Sindh Biotechnologist Association

For biomedical applications, 3-D printing has established its appreciable potential in the production of functional scaffolds. Day by day increase in advancement in the techniques of 3D printing gave rise to hope for enhancements in regenerative medication. The aim of this field of research is the use of stem cells and different techniques to replace and repair the injured organs, cells, or tissues. Basic concept of Tissue Engineering: In 1993, tissue engineering concept was formalized in a paper by two scientist Langer and Vacanti, applications and characteristics of biodegradable 3-D scaffolds were described in detailed (An, J. et al., 2015). Tissue engineering is a developing branch, in which tissue scaffolds are used for the development of new tissues and these tissues used for various medical purposes. After many years of continuous efforts, a group of tissue culture, implantation replacement technologies have been established, which allows artificial extracellular fabricati...

Yes, literally,organs are being printed into its 3D replica. Why? In the United States, each patient is listed for an organ, every 15 minutes (Mandrycky et. al., 2016) and such increasing demand can’t be fulfilled. 3D bioprinting is an additive manufacturing technique, requiring   cells and biomaterials to construct a three dimensional structure of an organ or tissue with increased reproducibility ( meeting mechanistic and functionality) to native tissue. On the contrary, the conventional method has its limits in   reproducibility (Xia et. al.,2018). The   bioprinter comprises a computer attached to a machine. Knowing that a cell not only responds to hormones or nutrients or harmful molecules, but it also responds to its microenvironment. The structure of an extracellular environment, comprising different molecules, such as collagen and hyaluronic acid, thereby, maintaining structure of tissue. The adherence of a cell with its environment, signals a cell t...