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Showing posts with the label CRISPR

Lecture on the role of CRISPR CAS-9 in the treatment of HIV

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This lecture is presented by our volunteer Sajid Ali Shah, he is from Islamabad, Pakistan, and he is covering The role of CRISPR CAS-9 in the treatment of HIV. for video:  for slides: 

Lecture on CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)

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 This Lecture is presented by our volunteer Talha Saleem, he is from Karachi Pakistan, and he is covering CRISPR topic. For video:    For Slides:

CRISPR: A New Era

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    What Is CRISPR? CRISPR technology is a simple yet effective method for genome editing. It enables scientists to readily change DNA sequences and gene function. Correcting genetic abnormalities, curing and controlling the spread of diseases, and boosting crops are just a few of its many potential applications. However, its promise also raises ethical concerns. "CRISPR" (pronounced "crisper") is a popular abbreviat ion for "CRISPR - Cas9." "CRISPR" stands for "clusters of regularly interspaced short palindromic repeats." Discovery of CRISPRs CRISPRs are DNA sequences that repeat themselves in the genomes of prokaryotes like bacteria and archaea. CRISPRs were discover ed in E. coli in 1987 by Yoshizumi Ishino and his team, who were investigating a gene for alkaline phosphatase conversion when they accidently cloned a unique set of repetitive sequences inte rspersed with spacer sequences. [Is...

CRISPR and Its Applications

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Introduction Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), is a family of short sequences of DNA fragments found in the immune system of bacteria(50%) and archaea(90%) known as  CRISPR . These sequences are used to protect the immune system of prokaryotes against the viral infection by invading and cutting the viral DNA. These specific short sequences are actually derived from the part of the viral genome i.e. bacteriophage that infects the prokaryotes and now became the part of the prokaryotic genome which it uses as an antiviral property in the defence system. Now, scientists are able to alter the DNA of various organisms by using CRISPR technology as a  GENOME EDITING TOOL . By altering gene sequences and gene functions, CRISPR technology may allow to treat various disease including cancer and to improve agricultural crops. In 1987, Yoshizumi Ishino firstly discovered clustered repeats by cloning ‘iap’ gene along with CRISPR sequences but he did not ...