What Is CRISPR? CRISPR technology is a simple yet effective method for genome editing. It enables scientists to readily change DNA sequences and gene function. Correcting genetic abnormalities, curing and controlling the spread of diseases, and boosting crops are just a few of its many potential applications. However, its promise also raises ethical concerns. "CRISPR" (pronounced "crisper") is a popular abbreviat ion for "CRISPR - Cas9." "CRISPR" stands for "clusters of regularly interspaced short palindromic repeats." Discovery of CRISPRs CRISPRs are DNA sequences that repeat themselves in the genomes of prokaryotes like bacteria and archaea. CRISPRs were discover ed in E. coli in 1987 by Yoshizumi Ishino and his team, who were investigating a gene for alkaline phosphatase conversion when they accidently cloned a unique set of repetitive sequences inte rspersed with spacer sequences. [Is...