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Transgenic animals are those animals whose genetic makeup has been altered by the insertion or deletion of genes under specific conditions. These genetically modified organisms are widely used in the field of biology, healthcare, scientific research, agriculture and pharmaceutical industry etc. New and advanced technologies are used to produce new recombinant genes and these methods have many advantages but at the same time, they have certain drawbacks as well. With that, transgenic animals have their DNA altered in such a way that they contain foreign DNA incorporated in them which is unnaturally introduced in their genome. The bacteria Escherichia coli was the first organism whose genome was manipulated through artificial means. This led to significant advances in genome modification technology and ultimately led to the production of transgenic animals. The first such transgenic animals were mice. Genome modification of mice led to the interpretation and techniques of genetic en...

Transgenic animals are commonly known as “Genetically Engineered Organism” (GEO) or “Genetically Modified Organism” (GMO). The advancement in biological science to produce genetically modified animals by introducing a foreign gene into the animal germ-line has raised the strength of bioresearch to an unexpected level (Datta, S., et al, 2018). The transgenic technique gives a very beneficial method to quickly introduce modified genes into the host genome without cross-breeding (Mohammed, F., et al, 2016). The transgenic technology emergence has broadened the development scope in the farm animal’s case and the arrival of new techniques of molecular biology have paved the way by giving the latest aspects to animal breeding ( Rajoriya. R ., et al., 2013). What are transgenic animals? The transgenic animal is a modified animal that carrying a modified gene that has been intentionally admitted into an animal genome. Transgenesis refers to Complementary Deoxyribonucleic Acid (cDNA) inser...