Welcome to Sindh Biotechnologist Association

By: Zobiya Ameen Introduction Since the discovery of mRNA 3 decades ago, and with extensive research, it has gained popularity in the scientific community after the successful application of mRNA Vaccines for the COVID-19 Pandemic. mRNA, also known as messenger RNA, is a molecule that holds the instructions or protocol that tells the cells to use their natural machinery to build a protein.   The current emphasis in regenerative medicine is on mRNA technology, which utilizes cellular programming and genetic manipulation to address degenerative diseases and facilitate tissue regeneration (Chabanovska et al., 2021). In Regenerative medicine, Significant advances made to harness stem cells’ therapeutic ability and their intrinsic regenerating capacity upon tissue damage. Their ability to trans-differentiate and the potential for indefinite cell division is an asset (Mahla, 2016).   It complements the mRNA-based manipulation of somatic cells by editing, replacing, adding, o...

Survey On Impact Of Climate Change On Mental Health By: Amna Iftikhar Introduction: Throughout history, climate and weather have had an impact on human health. The environment that gives us clean air to breathe, food to eat, water to drink, shelter to live in, and security to live in is affected by changes in climate and climate variability, notably changes in weather extremes. The health and well-being of people are at risk from climate change and other natural and man-made stressors in many different ways. The concepts of climate and weather are often confused. Weather is the state of the atmosphere at any given time and place. Severe weather conditions include hurricanes, tornadoes, blizzards, and droughts. Climate is the average weather conditions that persist over multiple decades or longer. While the weather can change in minutes or hours, identifying a change in climate has required observations over a time period of decades to centuries or longer. Climate change encompa...

  By: Narmeen Maqsood GENE DRIVE TECHNOLOGY OF MOSQUITO TO PREVENT MALARIA : Gene drives are selfish genetic elements that can be re-designed to invade a population, and they hold tremendous potential for the control of mosquitoes that transmit disease. Much progress has been made recently in demonstrating proof of principle for gene drives able to suppress populations of malarial mosquitoes or to make them refractory to the Plasmodium parasites they transmit. Gene drives that are designed to spread and impose a suppressive effect on either the mosquito or the parasite it transmits are expected eventually, like any intervention, to select for resistance in each organism, respectively. (Nolan.,2020) Gene-drive-modified mosquitoes hold promise as new tools for the control and elimination of malaria and other mosquito-borne diseases. GDMMs aim to achieve area-wide control with characteristics that differ substantially from current insecticide-based mosquito control methods, rais...