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Parkinson's Disease

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Aging is one of the sad realities of life. With growing age when an individual exceeds in knowledge and wisdom, he/she also gets weaker and falls prey to many diseases. Aging is a result of cellular damage occurring with the passage of time. Parkinson’s disease is among several age-related diseases and is the second most common neurodegenerative disease around the globe. This disease is named after James Parkinson , who was a British physician, and first diagnosed it in the year 1817 and described it in his writing “An essay on the Shaking Palsy”. It is a progressive disease in which dopaminergic neurons have deteriorated mainly in a specific region of the brain called substantia nigra, which is critically important in controlling the motor functions of the body. This neurodegeneration of causes a deficiency of dopamine in CNS. Dopamine is a neurotransmitter responsible for carrying signals between neurons and its deficiency results in decreased control of muscular movement. This...