The Diagnosis and Treatment of Baroreflex Failure
The baroreflex, also known as the baroreceptor reflex, is a homeostatic system in the body that serves to keep blood pressure at approximately constant levels. The baroreflex creates a quick negative feedback loop in which increased blood pressure induces a reduction in heart rate. Reduced blood pressure reduces baroreflex activation, causing heart rate to increase and blood pressure to return to normal. Their role is to detect pressure changes by responding to variations in artery wall tension [1]. Anatomy of baroreflex : The carotid sinuses and aortic arch contain the most sensitive baroreceptors. The aortic arch baroreceptor axons travel inside the vagus nerve (CN X), whereas the carotid sinus baroreceptor axons travel within the glossopharyngeal nerve (CN IX). Baroreceptor activation passes directly into the central nervous system to stimulate glutamatergic neurons in the brainstem's solitary nucleus [2]. Baroreflex Therapy To Reduce Sympathetic Nerve Activity: The ...