Welcome to Sindh Biotechnologist Association

This lecture is presented by our volunteer Sajid Ali Shah, he is from Islamabad, Pakistan, and he is covering "Dengue Virus: Genomic Insights, Pathogenic Mechanisms, and Therapeutic Approaches". for Video:  for slides: Dengue Virus: Genomic Insights, Pathogenic Mechanisms, and Therapeutic Approaches from SindhBiotech

Introduction: Dengue is a mosquito-transmitted virus and the leading cause of arthropod-borne viral disease in the world. And is primarily transmitted to humans by the female  Aedes  mosquito. It is also known as break bone fever due to the severity of muscle spasms and joint pain, dandy fever, or seven-day fever because of the usual duration of symptoms. Although most cases are asymptomatic, severe illness and death may occur.  The incidence of dengue has increased dramatically over the past few decades. The infection is now endemic in some parts of the world. A few people who were previously infected with one subspecies of the dengue virus develop severe capillary permeability and bleeding after being infected with another subspecies of the virus. This illness is known as dengue hemorrhagic fever. Dengue fever virus (DENV) is an  RNA virus  of the family  Flaviviridae ; genus  Flavivirus . Other members of the same genus include ...