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TRANGENIC ANIMALS

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Transgenic animals are those animals whose genetic makeup has been altered by the insertion or deletion of genes under specific conditions. These genetically modified organisms are widely used in the field of biology, healthcare, scientific research, agriculture and pharmaceutical industry etc. New and advanced technologies are used to produce new recombinant genes and these methods have many advantages but at the same time, they have certain drawbacks as well. With that, transgenic animals have their DNA altered in such a way that they contain foreign DNA incorporated in them which is unnaturally introduced in their genome. The bacteria Escherichia coli was the first organism whose genome was manipulated through artificial means. This led to significant advances in genome modification technology and ultimately led to the production of transgenic animals. The first such transgenic animals were mice. Genome modification of mice led to the interpretation and techniques of genetic en...