Public opinion on aspects and ethical issues of xenotransplantation

By: Naveen Khan

Introduction;

The transplanting of living cells, tissues, or organs from one species to another is known as xenotransplantation (from the Greek word xenos, which means "foreign" or "strange"[1][2]). [3] Xenografts or xenotransplants are the terms used to describe such cells, tissues, or organs. When compared to autotransplantation (from one area of the body to another in the same person), syngeneic transplantation (grafts between two genetically identical individuals of the same species), and allotransplantation (from another individual of the same species), Midway through December 1996, at Sonapur, Assam, India, a non-genetically altered [12][13] pig's heart, lungs, and kidneys were transplanted into a human. The procedure was announced in January 1997. [12] Purno Saikia, a 32-year-old terminally ill man, was the receiver; shortly after the procedure, he passed away from various illnesses. [12] The operations were carried out by the Indian cardiothoracic surgeon Dhani Ram Baruah and two of his colleagues, Jonathan Ho Kei-shing (of the Prince of Wales Medical Institute in Hong Kong)[15] and C.S. James. [12] Saikia and his family had given their assent to the procedure, according to Baruah, who also stated that Saikia had not responded to traditional surgery. [16]

 

Objective of the study;

·         To find out the  public’s opinion about xenotransplantation

·         To find out the ratio of people who are in favors of xenotransplantation

·         To the knowledge of xenotransplantation to people 

 

Aim of the study

Xenotransplantation of now very common transplantation in overall world people are mostly  using pigs for xenotransplantation through this survey we are trying to find out what is people option related to xenotransplantation  what they think about transplantation this survey will be filled by different religion people we will survey their options about  xenotransplantation. Deeply troubling ethical questions surround xenotransplantation, both for the potential recipients and for society at large. In the past ten years, there have been more quantitative public opinion polls about xenotransplantation undertaken concurrently with growing scientific interest. The current study's objectives were to clarify these surveys and evaluate various aspects that might have an impact on their results.

References

v  Dooldeniya, M D; Warrens, AN (2003). "Xenotransplantation: where are we today?". Journal of the Royal Society of Medicine. 96 (3): 111–117. doi:10.1177/014107680309600303. PMC 539416. PMID 12612110.

v  Mitchell, C Ben (2000-05-10). "Xenotransplanation and Transgenics: The Need to Discuss Limits". Cbhd. CBHD. Retrieved 19 November 2018.

v  Xenotransplantation. Definition by the World Health Organization

v  Tentler, J. J.; Tan, A. C.; Weekes, C. D.; Jimeno, A; Leong, S; Pitts, T. M.; Arcaroli, J. J.; Messersmith, W. A.; Eckhardt, S. G. (2012). "Patient-derived tumour xenografts as models for oncology drug development". Nature Reviews. Clinical Oncology. 9 (6): 338–50. doi:10.1038/nrclinonc.2012.61. PMC 3928688. PMID 22508028.

v  Kress, J. M. (1998). "Xenotransplantation: Ethics and economics". Food and Drug Law Journal. 53 (2): 353–384. PMID 10346691.

v  Hoffman J, Valencak TG (2020). "A short life on the farm: aging and longevity in agricultural, large-bodied mammals". GeroScience. 42 (3): 909–922. doi:10.1007/s11357-020-00190-4. PMC 7286991. PMID 32361879.

v  "Interviews - Dan Lyons". PBS. Retrieved May 21, 2022.

v  "Organ Transplants from Animals: Examining the Possibilities". Fda.gov. Internet Archive. Archived from the original on December 10, 2007. Retrieved May 21, 2022.

v  Reemtsma, K (1995). "Xenotransplantation: A Historical Perspective". ILAR Journal. 37 (1): 9–12. doi:10.1093/ilar.37.1.9. PMID 11528018.

 

Introduction;

The transplanting of living cells, tissues, or organs from one species to another is known as xenotransplantation (from the Greek word xenos, which means "foreign" or "strange"[1][2]). [3] Xenografts or xenotransplants are the terms used to describe such cells, tissues, or organs. When compared to autotransplantation (from one area of the body to another in the same person), syngeneic transplantation (grafts between two genetically identical individuals of the same species), and allotransplantation (from another individual of the same species), Midway through December 1996, at Sonapur, Assam, India, a non-genetically altered [12][13] pig's heart, lungs, and kidneys were transplanted into a human. The procedure was announced in January 1997. [12] Purno Saikia, a 32-year-old terminally ill man, was the receiver; shortly after the procedure, he passed away from various illnesses. [12] The operations were carried out by the Indian cardiothoracic surgeon Dhani Ram Baruah and two of his colleagues, Jonathan Ho Kei-shing (of the Prince of Wales Medical Institute in Hong Kong)[15] and C.S. James. [12] Saikia and his family had given their assent to the procedure, according to Baruah, who also stated that Saikia had not responded to traditional surgery. [16]

 

Objective of the study;

·         To find out the  public’s opinion about xenotransplantation

·         To find out the ratio of people who are in favors of xenotransplantation

·         To the knowledge of xenotransplantation to people 

 

Aim of the study

Xenotransplantation of now very common transplantation in overall world people are mostly  using pigs for xenotransplantation through this survey we are trying to find out what is people option related to xenotransplantation  what they think about transplantation this survey will be filled by different religion people we will survey their options about  xenotransplantation. Deeply troubling ethical questions surround xenotransplantation, both for the potential recipients and for society at large. In the past ten years, there have been more quantitative public opinion polls about xenotransplantation undertaken concurrently with growing scientific interest. The current study's objectives were to clarify these surveys and evaluate various aspects that might have an impact on their results.

References

v  Dooldeniya, M D; Warrens, AN (2003). "Xenotransplantation: where are we today?". Journal of the Royal Society of Medicine. 96 (3): 111–117. doi:10.1177/014107680309600303. PMC 539416. PMID 12612110.

v  Mitchell, C Ben (2000-05-10). "Xenotransplanation and Transgenics: The Need to Discuss Limits". Cbhd. CBHD. Retrieved 19 November 2018.

v  Xenotransplantation. Definition by the World Health Organization

v  Tentler, J. J.; Tan, A. C.; Weekes, C. D.; Jimeno, A; Leong, S; Pitts, T. M.; Arcaroli, J. J.; Messersmith, W. A.; Eckhardt, S. G. (2012). "Patient-derived tumour xenografts as models for oncology drug development". Nature Reviews. Clinical Oncology. 9 (6): 338–50. doi:10.1038/nrclinonc.2012.61. PMC 3928688. PMID 22508028.

v  Kress, J. M. (1998). "Xenotransplantation: Ethics and economics". Food and Drug Law Journal. 53 (2): 353–384. PMID 10346691.

v  Hoffman J, Valencak TG (2020). "A short life on the farm: aging and longevity in agricultural, large-bodied mammals". GeroScience. 42 (3): 909–922. doi:10.1007/s11357-020-00190-4. PMC 7286991. PMID 32361879.

v  "Interviews - Dan Lyons". PBS. Retrieved May 21, 2022.

v  "Organ Transplants from Animals: Examining the Possibilities". Fda.gov. Internet Archive. Archived from the original on December 10, 2007. Retrieved May 21, 2022.

v  Reemtsma, K (1995). "Xenotransplantation: A Historical Perspective". ILAR Journal. 37 (1): 9–12. doi:10.1093/ilar.37.1.9. PMID 11528018.

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